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Why do stomach ulcers hurt after meals

2025-09-29 15:36:42 healthy

Why do stomach ulcers hurt after meals

Gastric ulcer is a common digestive disorder, and one of its main symptoms is postprandial pain. This pain usually occurs within 30 minutes to 2 hours after eating, seriously affecting the patient's quality of life. This article will analyze the causes of postprandial pain of gastric ulcer from the aspects of the pathogenesis, symptoms, diagnosis methods and treatment suggestions of gastric ulcer in detail.

1. The pathogenesis of gastric ulcer

Why do stomach ulcers hurt after meals

The occurrence of gastric ulcer is related to a variety of factors, mainly including excessive gastric acid secretion, impaired gastric mucosal barrier function, and Helicobacter pylori infection. The following is a brief summary of the pathogenesis of gastric ulcer:

factorMechanism of action
Excessive secretion of gastric acidGastric acid directly corrodes the gastric mucosa, causing ulcers to form
Impaired gastric mucosal barrier functionMucosal defense ability is reduced and cannot resist gastric acid erosion
Helicobacter pylori infectionBacteria destroy gastric mucosa, causing inflammation and ulcers
Nonsteroidal anti-inflammatory drugs (NSAIDs)Inhibit prostaglandin synthesis and weaken mucosal protection

2. Why does gastric ulcer hurt after meals?

Postprandial pain is one of the typical symptoms of gastric ulcer, and its mechanism is mainly related to the following factors:

1.Increased gastric acid secretion: After eating, the amount of gastric acid secretion increases significantly, especially high-protein or high-fat foods will stimulate gastric acid secretion. Gastric acid directly acts on the ulcer surface, stimulating nerve endings and causing pain.

2.Food rubbing ulcer surface: After eating, food may rub against the ulcer surface during intragastric peristalsis, aggravate local damage and cause pain.

3.Changes in the stomach pressure: Increased pressure in the stomach after meals may cause mechanical irritation to the ulcer surface and cause pain.

4.Delayed gastric emptying: Some patients with gastric ulcers are accompanied by gastric emptying disorders, and the food stays in the stomach for a longer time, which continuously stimulates the ulcer surface.

3. Other symptoms of gastric ulcer

In addition to postprandial pain, gastric ulcers may also be accompanied by the following symptoms:

symptomIncidence rateFeatures
Upper abdominal pain80%-90%Mostly burning or dull pain, which worsens after meals
Acid reflux60%-70%Reflux of stomach contents to the esophagus
Belching50%-60%Frequent hiccups
Nausea and vomiting30%-40%In severe cases, blood may be vomited
Loss of appetite40%-50%Fear of eating due to pain

4. Diagnosis of gastric ulcer

Confirming gastric ulcer requires combining clinical symptoms and auxiliary examinations. The following are commonly used diagnostic methods:

1.Gastroscopy: It is the gold standard for diagnosing gastric ulcers. It can directly observe the size, shape and location of the ulcer, and a biopsy can be performed.

2.Helicobacter pylori detection: Including urea breath test, fecal antigen detection and histological examination, etc.

3.X-ray barium meal examination: Suitable for patients who cannot tolerate gastroscopy, it can display ulcer niche shadows.

4.Laboratory inspection: Including routine blood, stool occult blood tests, etc., to evaluate the presence or absence of anemia and bleeding.

5. Suggestions for treating gastric ulcers

The treatment of gastric ulcer requires a multi-pronged approach, mainly including the following aspects:

Treatment measuresSpecific methodsThings to note
Drug treatmentProton pump inhibitor, H2 receptor antagonist, gastric mucosal protective agent, antibiotics (Helicobacter pylori positive)Take medication according to the doctor's instructions and complete the full treatment
Dietary adjustmentEat less and eat more, avoid irritating foods, quit smoking and limit alcoholChew slowly to avoid overfilling
Lifestyle changesRegular work and rest to reduce stress and avoid NSAIDsStay happy
Surgical treatmentSuitable for complications (perforation, bleeding, obstruction) or refractory ulcersStrictly grasp the surgical indications

6. Daily suggestions for preventing gastric ulcers

1. Maintain dietary rules and avoid overeating.

2. Reduce the intake of irritating foods such as spicy, greasy, and overacid.

3. Quit smoking and limit alcohol, and reduce irritation to the gastric mucosa.

4. Use NSAIDs drugs reasonably, and if necessary, combine with gastric mucosa protective agents under the guidance of a doctor.

5. Manage pressure and maintain a good attitude.

6. Regular physical examinations, especially those with a family history of stomach problems.

Conclusion

Postprandial pain in gastric ulcer is a complex pathophysiological process, which is mainly related to factors such as gastric acid secretion, food stimulation and changes in gastric motility. Through standardized treatment and lifestyle adjustments, most patients with gastric ulcers can obtain a good prognosis. If you often experience symptoms such as postprandial upper abdominal pain, it is recommended to seek medical treatment in time to avoid delaying diagnosis and treatment.

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